{"id":38500,"date":"2025-01-10T13:45:00","date_gmt":"2025-01-10T13:45:00","guid":{"rendered":"https:\/\/www.lifeandnews.com\/articles\/?p=38500"},"modified":"2025-01-11T07:49:52","modified_gmt":"2025-01-11T07:49:52","slug":"even-1-drink-a-day-elevates-your-cancer-risk-an-expert-on-how-alcohol-affects-the-body-breaks-down-a-new-government-report","status":"publish","type":"post","link":"https:\/\/www.lifeandnews.com\/articles\/even-1-drink-a-day-elevates-your-cancer-risk-an-expert-on-how-alcohol-affects-the-body-breaks-down-a-new-government-report\/","title":{"rendered":"Even 1 drink a day elevates your cancer risk \u2013 an expert on how alcohol affects the body breaks down a new government&nbsp;report"},"content":{"rendered":"\n<p><a href=\"https:\/\/theconversation.com\/profiles\/nikki-crowley-1525245\">Nikki Crowley<\/a>, <em><a href=\"https:\/\/theconversation.com\/institutions\/penn-state-1258\">Penn State<\/a><\/em><\/p>\n\n\n\n<p>Many people use the new year to reflect on their relationship with alcohol. Just-released government guidelines are giving Americans another reason to consider a \u201c<a href=\"https:\/\/www.niaaa.nih.gov\/about-niaaa\/directors-page\/niaaa-directors-blog\/kicking-new-year-dry-january-here-are-six-tips-success\">dry January<\/a>.\u201d<\/p>\n\n\n\n<p>Over the past few decades, mounting scientific evidence has shown that as little as 1-2 alcoholic drinks per day can lead to increases in the likelihood of <a href=\"https:\/\/doi.org\/10.1038\/bjc.2014.579\">several cancers<\/a>. This prompted the U.S. surgeon general, Dr. Vivek Murthy, to release a <a href=\"https:\/\/www.hhs.gov\/surgeongeneral\/priorities\/alcohol-cancer\/index.html\">new Surgeon General Advisory on Jan. 3, 2025<\/a>, warning about the link between alcohol and cancer. This report highlighted the evidence and included a call for <a href=\"https:\/\/www.hhs.gov\/about\/news\/2025\/01\/03\/us-surgeon-general-issues-new-advisory-link-alcohol-cancer-risk.html\">new cancer warning labels<\/a> on alcoholic beverages.<\/p>\n\n\n\n<p>The association between alcohol and cancer isn\u2019t new news \u2013 scientists have been <a href=\"https:\/\/aacrjournals.org\/cancerres\/article\/52\/7_Supplement\/2119s\/498659\/Alcohol-and-Cancer1\">trying to determine the link for decades<\/a> \u2013 yet most people aren\u2019t aware of the risks and may only associate drinking with <a href=\"https:\/\/doi.org\/10.14309\/ajg.0000000000000340\">liver disease like cirrhosis<\/a>. In a 2019 survey from the American Institute for Cancer Research, less than half of Americans identified <a href=\"https:\/\/www.aicr.org\/news\/survey-finds-alarming-gaps-in-americans-knowledge-of-major-cancer-risk-factors\/\">alcohol as a risk factor for cancer<\/a>.<\/p>\n\n\n\n<p>Alcohol is the third-most preventable cause of cancer in the U.S, putting it just behind tobacco and obesity. As the surgeon general\u2019s report highlights, alcohol is associated with approximately <a href=\"https:\/\/doi.org\/10.3322\/caac.21858\">100,000 cancer cases and 20,000 cancer deaths every year<\/a>, playing a role in breast, liver, colorectal, mouth, throat, esophagus and voice box cancer cases. Alcohol-induced cancer deaths outnumber <a href=\"https:\/\/crashstats.nhtsa.dot.gov\/Api\/Public\/ViewPublication\/813435\">alcohol-associated traffic crash fatalities<\/a> every year.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img src=\"https:\/\/images.theconversation.com\/files\/641090\/original\/file-20250107-15-yd50gv.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip\" alt=\"A diagram of the human body showing the seven types of cancer caused by drinking.\" \/><figcaption>The increase in alcohol-induced breast cancer is a particular worry. <a href=\"https:\/\/www.hhs.gov\/surgeongeneral\/priorities\/alcohol-cancer\/index.html\">Office of the U.S. Surgeon General<\/a><\/figcaption><\/figure>\n\n\n\n<p>The report included the suggestion to add warning labels to alcohol similar to what is already required for tobacco products \u2013 <a href=\"https:\/\/doi.org\/10.1038\/nrc1190\">another substance of abuse known to cause cancer<\/a>.<\/p>\n\n\n\n<p>As a <a href=\"https:\/\/www.huck.psu.edu\/people\/nikki-crowley\">neuroscientist<\/a> specializing in the <a href=\"https:\/\/scholar.google.com\/citations?user=I6cQzksAAAAJ&amp;hl=en\">neurobiological effects of alcohol use and binge drinking<\/a>, I am glad to see the call to action for reducing alcohol consumption in the United States.<\/p>\n\n\n\n<h2>Key takeaways of the report<\/h2>\n\n\n\n<p>With so few people aware of the links between alcohol consumption and various cancers \u2013 and the fact that the <a href=\"https:\/\/arg.org\/news\/updated-us-drinking-norms-2020-data\/\">vast majority of people consume some alcohol every week<\/a> \u2013 it\u2019s easy to see why the surgeon general is calling for greater awareness. The <a href=\"https:\/\/www.hhs.gov\/sites\/default\/files\/oash-alcohol-cancer-risk.pdf\">22-page report<\/a> highlights what scientists know about the relationship between alcohol and cancer, and suggests actions for moving forward. Those include label changes on alcohol, which have not been updated since they were created in 1988.<\/p>\n\n\n\n<p>Somewhat strikingly, breast cancer carries a large portion of this risk \u2013 making it particularly worrisome in the face of <a href=\"https:\/\/theconversation.com\/binge-drinking-is-a-growing-public-health-crisis-a-neurobiologist-explains-how-research-on-alcohol-use-disorder-has-shifted-227313\">increased alcohol use among women<\/a>.<\/p>\n\n\n\n<p>These numbers don\u2019t only apply to heavy alcohol drinkers. While less alcohol is better, 25% of these cancer cases were in people <a href=\"https:\/\/www.thelancet.com\/journals\/lanonc\/article\/PIIS1470-2045(21)00279-5\/fulltext\">classified as moderate drinkers<\/a> \u2013 consuming, on average, fewer than two drinks per day. This means that anyone regularly drinking alcohol, even small amounts, should know about and understand the risks.<\/p>\n\n\n\n<p>Surgeon general\u2019s advisories are the primary way that the Department of Health and Human Services, where the Office of the Surgeon General resides, communicate health issues of great importance to the public. Surgeon general\u2019s advisories are not necessarily breaking news, but they take the opportunity to bring public awareness to science surrounding big public health issues.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img src=\"https:\/\/images.theconversation.com\/files\/641074\/original\/file-20250107-15-973kuc.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip\" alt=\"A diagram showing that the majority of Americans don't know that alcohol increases cancer risk.\" \/><figcaption>Many Americans will be surprised by the conclusions of the surgeon general\u2019s report. <a href=\"https:\/\/www.hhs.gov\/surgeongeneral\/priorities\/alcohol-cancer\/index.html\">Office of the U.S. Surgeon General<\/a><\/figcaption><\/figure>\n\n\n\n<h2>The science behind the link between alcohol and cancer<\/h2>\n\n\n\n<p>The relationship between alcohol and cancer has been clear to scientists for decades. In fact, it was highlighted in a 2016 surgeon general\u2019s report as well, which <a href=\"https:\/\/store.samhsa.gov\/product\/facing-addiction-america-surgeon-generals-report-alcohol-drugs-and-health-full-report\/sma16-4991\">focused on addiction more broadly<\/a>.<\/p>\n\n\n\n<p>The <a href=\"https:\/\/www.hhs.gov\/sites\/default\/files\/oash-alcohol-cancer-risk.pdf\">new report outlines the different types of evidence<\/a> supporting this link. One way is through <a href=\"https:\/\/doi.org\/10.1158\/1055-9965.EPI-21-0934\">epidemiological science<\/a>, which tries to understand patterns and relationships between <a href=\"https:\/\/doi.org\/10.1111\/add.13477\">the rates of cancer and how much alcohol people consumed<\/a>. Another is through experimental animal studies, which allow scientists to understand the mechanism and causality of these connections as they apply to <a href=\"https:\/\/doi.org\/10.1016\/j.oraloncology.2005.07.014\">specific cancers<\/a>. Together, studies conclusively show a link and pathway between alcohol consumption and cancer.<\/p>\n\n\n\n<p>The surgeon general\u2019s report highlights four key pathways through which alcohol can cause cancer. These largely focus on the ways alcohol can negatively affect your DNA, the building blocks of cells. While the healthy cells in your body divide all the time, their abnormal growth can be driven by aberrant factors like alcohol-induced DNA damage.<\/p>\n\n\n\n<p>This DNA damage leads to <a href=\"https:\/\/www.cancer.gov\/about-cancer\/understanding\/what-is-cancer\">uncontrollable growth of tissue<\/a> instead of healthy, normal tissue growth. This abnormal tissue growth is cancer. The four pathways through which alcohol can lead to cancer highlighted in the report are:<\/p>\n\n\n\n<ol><li>The body naturally breaks alcohol down into acetaldehyde. Acetaldehyde <a href=\"https:\/\/doi.org\/10.1038\/nature25154\">can damage and break DNA<\/a>, leading to chromosomal rearrangements and tumors. This link is so strong that acetaldehyde has been <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17718399\/\">classified as a carcinogen since 1999<\/a>.<\/li><li>Alcohol creates reactive oxygen species. Reactive oxygen species, sometimes called \u201cfree radicals,\u201d are unstable molecules that contain oxygen and <a href=\"https:\/\/www.cancer.gov\/about-cancer\/causes-prevention\/risk\/alcohol\/alcohol-fact-sheet\">can further damage DNA, proteins and fats<\/a>.<\/li><li>Alcohol can influence hormones, like estrogen. Alcohol can raise the <a href=\"https:\/\/www.cancer.org\/cancer\/risk-prevention\/diet-physical-activity\/alcohol-use-and-cancer.html#\">amount of estrogen in the body<\/a>, which may explain its link to breast cancer. This increased estrogen can influence breast tissue by causing \u2013 you guessed it \u2013 DNA damage.<\/li><li>Alcohol is a solvent, which means other things can dissolve in it. This makes it easier for carcinogens from other sources \u2013 like cigarettes and e-vapes \u2013 <a href=\"https:\/\/www.cancervic.org.au\/cancer-information\/preventing-cancer\/limit-alcohol\/how-alcohol-causes-cancer#\">to be absorbed by the body<\/a> when the two are consumed together.<\/li><\/ol>\n\n\n\n<figure class=\"wp-block-image\"><img src=\"https:\/\/images.theconversation.com\/files\/641095\/original\/file-20250108-17-vc98za.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip\" alt=\"A diagram that shows how higher alcohol consumption increases cancer risk.\" \/><figcaption>The more you drink alcohol, the more you are at risk. <a href=\"https:\/\/www.hhs.gov\/surgeongeneral\/priorities\/alcohol-cancer\/index.html\">Office of the U.S. Surgeon General<\/a><\/figcaption><\/figure>\n\n\n\n<h2>Is any amount of alcohol safe?<\/h2>\n\n\n\n<p>The biggest question on people\u2019s minds right now is likely \u201chow much alcohol can I safely drink?\u201d and the answer to that might disappoint you \u2013 probably none.<\/p>\n\n\n\n<p>Alcohol use remains one of the most <a href=\"https:\/\/www.cancer.org\/cancer\/risk-prevention\/diet-physical-activity\/alcohol-use-and-cancer.html\">preventable risk factors for cancer<\/a>. And even moderate alcohol consumption \u2013 one or fewer drinks per day \u2013 may elevate cancer risk for some types, such as breast, throat and mouth cancers.<\/p>\n\n\n\n<p>But none of these studies can tell you what your individual risk for cancer is. The relationship between alcohol and cancer can be influenced by your genes, such as those that control the <a href=\"https:\/\/doi.org\/10.1016\/S1470-2045(09)70019-1\">enzymes that metabolize alcohol<\/a>, and other lifestyle factors that influence the rates of cancer broadly, like <a href=\"https:\/\/www.mdanderson.org\/prevention-screening\/manage-your-risk\/diet.html\">diet and inflammation<\/a>. All of these lifestyle and personal health factors can influence how risky alcohol consumption is for you.<\/p>\n\n\n\n<p>The Centers for Disease Control and Prevention notes that if you choose to drink, consider sticking to less than one, for women, or two, for men, <a href=\"https:\/\/www.prevention.va.gov\/Healthy_Living\/Limit_Alcohol.asp#:%7E:\">standard servings of alcohol per day<\/a> \u2013 <a href=\"https:\/\/www.niaaa.nih.gov\/alcohols-effects-health\/what-standard-drink\">which might be smaller than you think<\/a>, and don\u2019t binge drink alcohol at all. The surgeon general is also suggesting a rethinking of these guidelines to include updated limits on daily alcohol consumption and greater educational efforts around the link between alcohol and cancer.<\/p>\n\n\n\n<p>The National Institute on Alcohol Abuse and Alcoholism has similar recommendations around limiting alcohol consumption and advises that for people who choose to drink alcohol, \u201c<a href=\"https:\/\/www.niaaa.nih.gov\/health-professionals-communities\/core-resource-on-alcohol\/basics-defining-how-much-alcohol-too-much#pub-toc2\">the less, the better<\/a>.\u201d<\/p>\n\n\n\n<p>The institute <a href=\"https:\/\/rethinkingdrinking.niaaa.nih.gov\/\">offers tips on its website<\/a> for managing your alcohol consumption or abstaining from alcohol consumption altogether, including finding alternative hobbies and activities, identifying what leads to your urges to drink and having a plan to handle urges, and identifying a strategy for saying \u201cno\u201d to an alcoholic beverage in social settings.<\/p>\n\n\n\n<p><a href=\"https:\/\/theconversation.com\/profiles\/nikki-crowley-1525245\">Nikki Crowley<\/a>, Assistant Professor of Biology, Biomedical Engineering and Pharmacology, <em><a href=\"https:\/\/theconversation.com\/institutions\/penn-state-1258\">Penn State<\/a><\/em><\/p>\n\n\n\n<p>This article is republished from <a href=\"https:\/\/theconversation.com\">The Conversation<\/a> under a Creative Commons license. Read the <a href=\"https:\/\/theconversation.com\/even-1-drink-a-day-elevates-your-cancer-risk-an-expert-on-how-alcohol-affects-the-body-breaks-down-a-new-government-report-246767\">original article<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nikki Crowley, Penn State Many people use the new year to reflect on their relationship with alcohol. Just-released government guidelines are giving Americans another reason to consider a \u201cdry January.\u201d Over the past few decades, mounting scientific evidence has shown that as little as 1-2 alcoholic drinks per day can lead to increases in the [&hellip;]<\/p>\n","protected":false},"author":56,"featured_media":38501,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[8025,7,42,10,296,36,3410,38],"tags":[165,2845,5166,12741,268,15920,885,891,886,860,15919],"_links":{"self":[{"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/posts\/38500"}],"collection":[{"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/users\/56"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/comments?post=38500"}],"version-history":[{"count":1,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/posts\/38500\/revisions"}],"predecessor-version":[{"id":38502,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/posts\/38500\/revisions\/38502"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/media\/38501"}],"wp:attachment":[{"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/media?parent=38500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/categories?post=38500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifeandnews.com\/articles\/wp-json\/wp\/v2\/tags?post=38500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}